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Therapeutische toepassingen

van psychedelica in de GGZ

Malin Uthaug

Malin Uthaug, PhD

Maastricht University

A comparison of reactivation experiences following vaporization and intramuscular injection (IM) of synthetic 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting


Previous research suggests a therapeutic potential of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). However, online anecdotal reports have described a phenomenon following cessation of the acute effects of 5-MeO-DMT use which has been termed reactivation (i.e., re-experiencing [“flashback”]). To date, no research has investigated whether different routes of administration may confer different reactivation rates, effects and experiences.

The present study aimed to assess whether intramuscular injection (IM) and vaporization of 5-MeO-DMT conferred different reactivation rates, changes in satisfaction with life, as well as ratings of the experience with ego dissolution (EDI) and the mystical experience (MEQ).

Using internet-based advertisements, 27 respondents (Mage = 32. SE = 1.43; males = 18; North America = 19) completed an online-based survey.

Results will be summarized.


Malin completed her PhD at the department of Neuropsychology and Psychopharmacology, at the faculty of Psychology and Neuroscience at Maastricht University, The Netherlands. As part of her PhD, she investigated the short-term and long-term effects of Ayahuasca and 5-MeO-DMT in naturalistic settings, while simultaneously initiating several other studies on the psychedelic substance Mescaline and the breathing practice known as Holotropic Breathwork (HB).Malin is currently working as a Postdoctoral researcher at The Centre for Psychedelic Research, at Imperial College London, led by Dr. Robin Carhart-Harris. Here she is investigating the effects of 5-MeO-DMT and Holotropic Breathwork on mental health related variables, emobodiment, brain activity and consciousness.

Besides being a researcher, Malin is also a scientific advisor for Entheon Biomedical, an editor for the ‘Journal of Psychedelics Studies’, a board member of the American podcast-show known as Psychedelics Today, and the co-founder of the Norwegian Association for Psychedelic Science (Norsk Forening for Psykedelisk Vitenskap [NFPV]) whose main aim is to educate the general public as well as researchers, and mental health practitioners in Norway about psychedelics.