Laboratory research at Johns Hopkins School of Medicine has included administering psilocybin to healthy volunteers, psychologically distressed cancer patients, cigarette smokers seeking abstinence, ordained clergy, as well as beginner and long-term meditators.
The results from several studies suggest that mystical-type experiences appear to mediate sustained positive changes in attitudes, mood, and behavior.
However, individuals responding to a “bad trip” survey on the internet affirmed concerns about psilocybin ingestion in uncontrolled settings, potentially leading to acute psychological distress, risky behavior, or enduring psychological symptoms. But when psilocybin is given in laboratory studies to screened, prepared, and supported participants, the incidence of risky behavior or enduring psychological distress is extremely low.
This video, filmed at ICPR2016, highlights some past results of psilocybin studies from the Johns Hopkins Psilocybin Research Project, which started almost 20 years ago. The clip is from a key note speech given by Professor Roland R. Griffiths from the Johns Hopkins University School of Medicine.