Friederike Holze

Dr. Friederike Holze received her MSc in Pharmacy from the University of Basel in 2016. During her Master’s she worked in the Psychopharmacology research lab of Prof. Matthias E. Liechti at the University Hospital Basel where she conducted a clinical study investigating the emotional and social cognitive effects of alcohol. In 2017, she rejoined the research group of Prof. Matthias Liechti where she received her PhD in 2021 and where she is currently affiliated as postdoctoral researcher. Her research interests lie in the pharmacology of psychoactive substances, in particular psychedelics. She conducted several Phase I studies investigating the pharmacokinetics and pharmacodynamics of LSD and established a dose-effect relationship in doses from 5-200 µg. Additionally, she described the distinct acute pharmacological effects of LSD, MDMA and d-amphetamine. In this function, she has accompanied over 200 psychedelic experiences in healthy test subjects. Furthermore, she is involved in a Phase II study investigating the potential therapeutic effects of LSD in patients suffering from anxiety disorders.